Targeting cardiac fibrosis with engineered T cells
Abstract
Adoptive transfer of CAR T cells against the fibroblast marker FAP reduces cardiac fibrosis and restores function after cardiac injury in mice, providing proof-of-principle for the development of immunotherapeutic treatments for cardiac disease.
Type
Publication
Nature
Ricardo Linares Saldana
MD PhD
My research interests include distributed robotics, mobile computing and programmable matter.